AUGUST, 2014 Gene-Related Patents Issued - Full patent:
Pat No Title Assignee Date Issued Country
8,809,051 Transgenic mammals having human Ig loci including plural V.sub.H and V.sub..kappa. regions and antibodies produced therefrom Amgen Fremont Inc. 19-Aug-14 United States
8,795,960 Optimization of gene expression analysis using immobilized capture probes Bioarray Solutions, Ltd. 5-Aug-14 United States
8,802,437 Meganuclease reagents of uses thereof for treating genetic diseases caused by frame shift/non sense mutations Cellectis 12-Aug-14 France
8,802,431 Population of multipotent cardiac precursor cells derived from human blastocysts derived stem cells Cellectis AB 12-Aug-14 Germany
8,802,374 Truncated epiderimal growth factor receptor (EGFRt) for transduced T cell selection City of Hope 12-Aug-14 United States
8,802,393 Arabinose isomerase expressed from Corynebacterium genus and tagatose manufacturing method by using it CJ Cheiljedang Corporation 12-Aug-14 Korea
8,815,587 Postpartum cells derived from umbilical tissue and methods of making and using the same DePuy Synthes Products, LLC 26-Aug-14 United States
8,802,415 Talaromyces transformants DSM IP Assets B.V 12-Aug-14 Netharlands
8,809,030 Perhydrolase variant providing improved specific activity E. I. du Pont de Nemours and Company 19-Aug-14 United States
8,809,060 Ethanol-resistant yeast gene, and use thereof Ewha University-Industry Collaboration Foundation 19-Aug-14 United States
8,808,983 shRNA molecules and methods of use thereof Gradalis, Inc. 19-Aug-14 United States
8,802,367 Methods for quantitative cDNA analysis in single-cell Hitachi, Ltd. 12-Aug-14 Japan
8,808,992 SHOC2 mutations causing noonan-like syndrome with loose anagen hair Icahn School of Medicine at Mount Sinai 19-Aug-14 United States
8,809,048 Plasmid vector Independent Administrative Institution, Japan Agency for Marine-Earth Science and Technology 19-Aug-14 Japan
8,795,987 Ribonucleic acid interference molecules of Oryza sativa International Business Machines Corporation 5-Aug-14 United States
8,802,642 Spinal muscular atrophy treatment via targeting SMN2 catalytic core Iowa State University Research Foundation, Inc. 12-Aug-14 United States
8,795,962 Expression vectors based on modified ribosomal protein promoters and uses thereof in post-transcriptional assessment King Faisal Specialist Hospital and Research Center 5-Aug-14 Saudi Arabia
8,796,016 RNA interference mediating small RNA molecules Max-Planck-Gesellschaft zur Forderung der Wissenschaften E.V. 5-Aug-14 Germany
8,815,541 Method for making polypeptides Novo Nordisk A/S 26-Aug-14 Denmark
8,795,976 Gene and polypeptide relating to breast cancer OncoTherapy Science, Inc. 5-Aug-14 Japan
8,809,027 Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase OPX Biotechnologies, Inc. 19-Aug-14 United States
8,808,987 Method for identifying olfactory receptor included in one olfactory cell Panasonic Corporation 19-Aug-14 United States
8,815,540 Productivity augmenting protein factor, novel cell lines and uses thereof Probiogen AG 26-Aug-14 Germany
8,815,599 Methods and compositions for the inhibition of gene expression ProNAi Therapeutics, Inc. 26-Aug-14 United States
8,802,403 Method of preparation of a compound using a genetically modified homolactic thermophilic bacilli Purac Biochem B.V. 12-Aug-14 Netharlands
8,815,516 Methods for detecting gene dysregulation by intragenic differential expression Quest Diagnostics Investments Incorporated 26-Aug-14 United States
8,815,581 Method for proliferating stem cells by activating c-MET/HGF signaling and notch signaling Samsung Life Public Welfare Foundation 26-Aug-14 Korea
8,802,439 Methods for enhancing infectivity of retroviruses Saphire; Andrew 12-Aug-14 United States
8,795,988 Primer-extension based method for the generation of siRNA/miRNA expression vectors The Board of Regents for Oklahoma State University 5-Aug-14 United States
8,815,586 Modulation of gene expression using oligomers that target gene regions downstream of 3' untranslated regions The Board of Regents of the University of Texas System 26-Aug-14 United States
8,795,964 GRM3 mutations and use thereof for the diagnosis and treatment of melanoma The United States of America, as represented by the Secretary, Department of Health and Human Services 5-Aug-14 United States
8,795,958 In vivo gene sensors Trustees of Boston University 5-Aug-14 United States
8,802,416 Thermostable organic solvent tolerant protease from gram-positive bacteria Universiti Putra Malaysia 12-Aug-14 Malaysia
8,802,440 Therapeutic methods based on tyrosine-substituted, capsid-modified rAAV vectors University of Florida Research Foundation, Inc 12-Aug-14 United States
8,815,520 Method for discrimination of metaplasias from neoplastic or preneoplastic lesions Ventana Medical Systems, Inc. 26-Aug-14 United States
8,795,996 Genes related to xylose fermentation and methods of using same for enhanced biofuel production Wisconsin Alumni Research Foundation 5-Aug-14 United States
8,815,508 Method of identifying disease risk factors Zinfandel Pharmaceuticals, Inc. 26-Aug-14 United States
Pat No Title Assignee Date Issued Country
8,809,292 Compositions and methods for inhibiting expression of the PCSK9 gene Alnylam Pharmaceuticals, Inc 19-Aug-14 United States
8,809,293 Compositions and methods for inhibiting gene expression of hepatitis B virus Arrowhead Madison Inc. 19-Aug-14 United States
8,795,683 Vaccine formulations and uses thereof Baxter International Inc. 5-Aug-14 United States
8,795,681 Raccoon poxvirus expressing rabies glycoproteins Boehringer Ingelheim Vetmedica, Inc. 5-Aug-14 United States
8,809,291 Id-1 gene and gene products as therapeutic targets for treatment of breast cancer and other types of carcinoma California Pacific Medical Center Research Institute 19-Aug-14 United States
8,809,282 Method of reducing titers of antibodies specific for a therapeutic agent Duke University 19-Aug-14 United States
8,809,296 Apoptosis inducer for cancer cell Genecare Research Institute Co., Ltd. 19-Aug-14 Japan
8,796,236 Gene therapy for lysosomal storage diseases Genzyme Corporation 5-Aug-14 United States
8,809,297 Anticancer composition Korea Institute of Radiological & Medical Sciences 19-Aug-14 Korea
8,809,295 Composition containing inhibitors of the expression or activity of SH3RF2 for preventing or treating cancer Korea Research Institute of Bioscience and Biotechnology 19-Aug-14 Korea
8,802,648 Repressor on IFN-.lamda. promoter and siRNA against ZEB1 and BLIMP-1 to increase IFN-.lamda. gene activity Medical Diagnostic Laboratories, LLC 12-Aug-14 United States
8,796,239 Sirna compounds comprising terminal substitutions Quark Pharmaceuticals, Inc. 5-Aug-14 United States
8,802,720 Acylamino-substituted fused cyclopentanecarboxylic acid derivatives and their use as pharmaceuticals SANOFI 12-Aug-14 France
8,795,676 Genes encoding major capsid protein L1 of human papilloma virus Shanghai Zerun Biotechnology Co., Ltd. 5-Aug-14 China P. Rep.
8,808,684 Epidermal growth factor receptor (EGFR) and methods of use in adenoviral-associated virus type 6 (AAV6) transduction The United States of America, as represented by the Secretary, Department of Health and Human Services 19-Aug-14 United States
8,796,240 Cell growth inhibitor and screening method thereof The University of Tokyo 5-Aug-14 Japan
8,809,329 Detection and treatment of schizophrenia Tokyo Metropolitan Institute of Medical Science 19-Aug-14 Japan
8,802,109 Herpes simplex virus mutant ICP0 University of Kansas 12-Aug-14 United States
8,796,235 Methods for attenuating dengue virus infection University of South Florida 5-Aug-14 United States
Pat No Title Assignee Date Issued Country
8,798,341 Method and device for reading an emulsion Universite Pierre et Marie Curie 5-Aug-14 France
Pat No Title Assignee Date Issued Country
8,809,629 Modification of plant lignin content Arborgen Inc. 19-Aug-14 United States
8,796,507 MEG1 endosperm-specific promoters and genes Biogemma 5-Aug-14 France
8,802,929 MIR164 gene that controls plant root system development and fertility and use thereof Huazhong Agricultural University 12-Aug-14 China P. Rep.
8,809,619 Knockout mice for a P450 gene cluster ITI Scotland Limited 19-Aug-14 United Kingdom
8,809,628 S-adenosylmethionine synthetase expression elements identified from Arabidopsis thaliana Monsanto Technology LLC 19-Aug-14 United States
8,809,622 Methods and compositions for identifying downy mildew resistant cucumber plants Seminis Vegetable Seeds, Inc. 19-Aug-14 United States
8,796,506 Transgenic sugar beet plants Syngenta Participations AG 5-Aug-14 Switzerland
8,809,618 Transgenic mouse for screening and for studies of the pharmacodynamics and pharmacokinetics of ligands acting on the oestrogen receptor and its intracellular receptors, and method for the preparation thereof T.O.P. (Transgenic Operative Products) S.R.L. 19-Aug-14 Italy
8,796,505 Specific genetic modification of the activity of trehalose-6-phosphate synthase and expression in a homologous or heterologous environment Vlaams Interuniversitair Instituut Voor Biotechnologie V.Z.W. 5-Aug-14 Belgium
Pat No Title Assignee Date Issued Country
8,802,816 Method of obtaining a purified, biologically active heterologous protein Biocon Limited 12-Aug-14 India
8,796,421 Human epidermal growth factor receptor variant lacking an exon Shanghai Cancer Institute 5-Aug-14 China P. Rep.
Pat No Title Assignee Date Issued Country
8,796,444 Methods and compositions for the specific inhibition of gene expression by double-stranded RNA City of Hope 5-Aug-14 United States
8,809,515 Methods and compositions for the specific inhibition of gene expression by double-stranded RNA City of Hope 19-Aug-14 United States
8,809,514 Tripartite oligonucleotide complexes and methods for gene silencing by RNA interference GE Healthcare Dharmacon, Inc. 19-Aug-14 United States
Pat No Title Assignee Date Issued Country
8,802,867 Method for producing a sense RNA molecule Genisphere, LLC 12-Aug-14 United States
8,796,443 Reduced size self-delivering RNAi compounds RXi Pharmaceuticals Corporation 5-Aug-14 United States
8,796,440 Promote system for regulatable gene expression in mammalian cells The Brigham and Women's Hospital, Inc. 5-Aug-14 United States
Pat No Title Assignee Date Issued Country
8,805,545 Methods and apparatus for multi-vessel renal neuromodulation Medtronic Ardian Luxembourg S.a.r.l. 12-Aug-14 Luxembourg
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