| APRIL, 2014 Gene-Related Patents Issued - Full patent: http://patft.uspto.gov/netahtml/PTO/srchnum.htm | ||||
| CHEMISTRY: ANALYTICAL AND IMMUNOLOGICAL TESTING | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,703,496 | Biological markers for longevity and diseases and uses thereof | Albert Einstein College of Medicine of Yeshiva University | 22-Apr-14 | United States |
| CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,703,446 | Method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family | Ajinomoto Co., Inc. | 22-Apr-14 | Japan |
| 8,691,537 | Method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family with attenuated expression of the rcsA gene | Ajinomoto Co., Ltd. | 8-Apr-14 | Japan |
| 8,709,765 | Manipulation of an alternative respiratory pathway in photo-autotrophs | Aurora Algae, Inc. | 29-Apr-14 | United States |
| 8,685,723 | VCP-based vectors for algal cell transformation | Aurora Algae, Inc. | 1-Apr-14 | United States |
| 8,691,536 | Pectin lyase, pectin lyase polynucleotide, enzyme preparation, and method for producing single cells of plant tissue | Bio-I Co., Ltd. | 8-Apr-14 | Japan |
| 8,685,721 | Stable constitutively high expression vector for preparing HPV vaccine and recombinant lactic acid bacteria transformed thereby | Bioleaders Corporation | 1-Apr-14 | Korea |
| 8,691,782 | Single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton | BONAC Corporation | 8-Apr-14 | Japan |
| 8,703,469 | Baculoviruses with enhanced virion production and a method for the production of baculoviruses | Boyce Thompson Institute for Plant Research | 22-Apr-14 | United States |
| 8,691,540 | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans | Butamax Advanced Biofuels LLC | 8-Apr-14 | Germany |
| 8,709,782 | Targeted gene deletions for polysaccharide slime formers | C.P. Kelco U.S., Inc. | 29-Apr-14 | United States |
| 8,697,395 | Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof | Cellectis S.A. | 15-Apr-14 | France |
| 8,703,444 | Pichia pastoris deficient in endogenous secreted protease | Centre Hospitalier Universitaire Vaudois | 22-Apr-14 | Switzerland |
| 8,709,719 | ZNF217 a new prognostic and predictive biomarker of recurrent invasive and metastatic phenotypes in breast cancer | Centre Leon Berard | 29-Apr-14 | France |
| 8,709,766 | Use of endogenous promoters in genetic engineering of Nannochloropsis gaditana | Colorado School of Mines | 29-Apr-14 | United States |
| 8,685,677 | Detection of AAD-12 soybean event 416 | Dow AgroSciences, LLC. | 1-Apr-14 | United States |
| 8,697,354 | RNA-exit-channel: target and method for inhibition of bacterial RNA polymerase | Ebright; Richard H. | 15-Apr-14 | United States |
| 8,691,503 | Method and nucleic acids for the analysis of colorectal cell proliferative disorders | Epigenomics AG | 8-Apr-14 | Germany |
| 8,691,507 | Inhibitors of human EZH2 and methods of use thereof | Epizyme, Inc. | 8-Apr-14 | United States |
| 8,691,533 | Inducible gene expression | GeneArt AG | 8-Apr-14 | Germany |
| 8,697,394 | Production of modified glycoproteins having multiple antennary structures | Glycofi, Inc. | 15-Apr-14 | United States |
| 8,703,425 | Biomarker for gastric cancer | he Chinese University of Hong Kong | 22-Apr-14 | Hong Kong |
| 8,685,700 | Method for enhancing production polyhydroxyalkanoic acid from microorganism strains | Industry-Academic Cooperation Foundation Gyeongsang National University | 1-Apr-14 | United States |
| 8,709,799 | Lentiviral gene transfer vectors and their medicinal applications | Institut Pasteur | 29-Apr-14 | France |
| 8,691,527 | Substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system | Intrexon Corporation | 8-Apr-14 | United States |
| 8,691,514 | Method for selective control of helper T cell function | Japan Science and Technology Agency | 8-Apr-14 | Japan |
| 8,685,691 | Method for producing aminopeptidase | JCR Pharmaceuticals Co., Ltd. | 1-Apr-14 | Japan |
| 8,685,645 | Screening method and vector, vector library, and assay kit used therefor | Kabushiki Kaisha Toshiba | 1-Apr-14 | Japan |
| 8,691,505 | Promoter for use in transformation of algae | Kochi University | 8-Apr-14 | Japan |
| 8,697,415 | Deacetylation hydrolase of hyaluronic acid, hyaluronic acid deacetylated by same and derivative thereof | Korea Institute of Radiological & Medical Sciences | 15-Apr-14 | Korea |
| 8,685,671 | Process for producing recombinant glycoproteins by culturing a Hansenula polymorpha mutant strain | Korea Research Institute of Bioscience and Biotechnology | 1-Apr-14 | Korea |
| 8,709,812 | Drug comprising as the active ingredient proliferative vector containing survivin promoter | Kosai; Kenichiro | 29-Apr-14 | Japan |
| 8,685,701 | Recombinant Ralstonia eutropha capable of producing polylactic acid or polylatic acid compolymer, and method for producing polylactic acid or polylatic acid copolymer using same | LG Chem, Ltd. | 1-Apr-14 | Korea |
| 8,685,673 | Method for producing indole derivative | National Chiao Tung University | 1-Apr-14 | Taiwan |
| 8,685,653 | Method for stable gene-amplification in a bacterial host cell | Novozymes A/S | 1-Apr-14 | Denmark |
| 8,691,506 | Gene expression profiles being predictive for the response of tumors to pharmaceutically effective compounds | Oncotest GmbH | 8-Apr-14 | Germany |
| 8,685,641 | Method of screening compounds for treating bladder cancer | OncoTherapy Science, Inc. | 1-Apr-14 | Japan |
| 8,685,704 | Microorganism for the production of succinic acid | Organo-Balance GmbH | 1-Apr-14 | Germany |
| 8,703,481 | Episomal expression vector for metazoan cells | Ozer; Harvey L. | 22-Apr-14 | United States |
| 8,709,714 | Laminar library screen | Padgett; Hal S. | 29-Apr-14 | United States |
| 8,691,501 | Farnesyltransferase inhibitors for treatment of laminopathies, cellular aging and atherosclerosis | Progeria Research Foundation, Inc. | 8-Apr-14 | United States |
| 8,685,703 | Coryneform bacterium transformant having improved D-xylose-utilizing ability | Research Institute of Innovative Technology for the Earth | 1-Apr-14 | Japan |
| 8,709,721 | Fluorescent molecule and method for detecting target nucleic acid | Riken | 29-Apr-14 | Japan |
| 8,691,554 | Modified yeast consuming L-arabinose | Scandinavian Technology Group AB | 8-Apr-14 | Sweden |
| 8,697,427 | Recombinant microalgae cells producing novel oils | Solazyme, Inc. | 15-Apr-14 | United States |
| 8,697,358 | Non-invasive method for diagnosis of prostate cancer | Technische Universitaet Dresden | 15-Apr-14 | Germany |
| 8,697,359 | CRISPR-Cas systems and methods for altering expression of gene products | The Broad Institute, Inc. | 15-Apr-14 | United States |
| 8,697,381 | Methods for identifying modulators of RGS21 activity, compositions comprising an RGS21 Modulator, and methods of use thereof to modulate taste sensation | The Coca-Cola Company | 15-Apr-14 | United States |
| 8,685,660 | Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma | The Johns Hopkins University | 1-Apr-14 | United States |
| 8,685,687 | Chimeric zinc finger recombinases optimized for catalysis by directed evolution | The Scripps Research Institute | 1-Apr-14 | United States |
| 8,685,720 | Engineered cellular pathways for programmed autoregulation of differentiation | The Trustees of Princeton University | 1-Apr-14 | United States |
| 8,697,417 | Baculoviral vectors comprising repeated coding sequences with differential codon biases | Uniqure IP B.V. | 15-Apr-14 | Netherlands |
| 8,709,800 | Methods of isolating bipotent hepatic progenitor cells | University of North Carolina at Chapel Hill | 29-Apr-14 | United States |
| 8,691,579 | Methods of isolating bipotent hepatic progenitor cells | University of North Carolina at Chapel Hill | 8-Apr-14 | United States |
| 8,697,361 | Serotonin transporter gene and treatment of alcoholism | University of Virginia Patent Foundation | 15-Apr-14 | United States |
| 8,709,754 | Recombinant vectors for use in position-independent transgene expression within chromatin | University of Washington | 29-Apr-14 | United States |
| 8,709,720 | Methods and kits for predicting the responsiveness of hepatocellular carcinoma patients to 5-fluorouracil-based combination chemotherapy | Yeh; Chau-Ting | 29-Apr-14 | Taiwan |
| COMBINATORIAL CHEMISTRY TECHNOLOGY | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,697,607 | Generation and application of standardized universal libraries | Chen; Tao | 15-Apr-14 | Canada |
| DATA PROCESSING | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,700,335 | System and method for determining individualized medical intervention for a disease state | Caris MPI, Inc. | 15-Apr-14 | United States |
| 8,712,935 | Evolutionary clustering algorithm | Koninklijke Philips N.V. | 29-Apr-14 | Netherlands |
| DRUG | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,691,238 | High growth reassortant influenza A virus | Baxter Healthcare SA | 8-Apr-14 | Switzerland |
| 8,703,729 | Mixture comprising an inhibitor or suppressor of a gene and a molecule binding to an expression product of that gene | Biognostik Gesellschaft fur Biomolekulare Diagnostik mbH | 22-Apr-14 | Germany |
| 8,697,137 | Methods of using microspheres for active embolization | Biosphere Medical, Inc. | 15-Apr-14 | United States |
| 8,710,017 | Human and mouse targeting peptides identified by phage display | Board of Regents, The University of Texas Systems | 29-Apr-14 | United States |
| 8,703,161 | Skin repair compositions comprising circadian gene activators and a synergistic combination of Sirt1 gene activators | ELC Management, LLC | 22-Apr-14 | United States |
| 8,709,442 | Recombinant negative strand virus RNA expression systems and vaccines | ICAHN School of Medicine at Mount Sinai | 29-Apr-14 | United States |
| 8,691,785 | Compositions and methods for non-parenteral delivery of oligonucleotides | Isis Pharmaceuticals, Inc. | 8-Apr-14 | United States |
| 8,697,050 | Methods of treatment using a vector encoding p21/.sup.Cip1 | Miyasaka; Nobuyuki | 15-Apr-14 | Japan |
| 8,685,409 | Influenza T-cell immunization against diverse influenza A viruses | Mogam Biotechnology Research Institute | 1-Apr-14 | Korea |
| 8,710,003 | Treatment of diabetes with milk protein hydrolysate | Nestec S.A. | 29-Apr-14 | Switzerland |
| 8,709,397 | Avirulent oncolytic herpes simplex virus strains engineered to counter the innate host response | New York University | 29-Apr-14 | United States |
| 8,697,049 | Modified bacteriophage including an alpha/beta small acid-soluble spore protein (SASP) gene | Phico Therapeutics Ltd. | 15-Apr-14 | United Kingdom |
| 8,697,665 | Porphobilinogen deaminase gene therapy | Proyecto de Biomedicina CIMA S.L. | 15-Apr-14 | Spain |
| 8,685,368 | Polyamides for nucleic acid delivery | Reineke; Theresa M | 1-Apr-14 | United States |
| 8,703,731 | Sphingosine-bound siRNA | Sylentis S.A.U. | 22-Apr-14 | Spain |
| 8,709,412 | Modulation of TIM receptor activity in combination with cytoreductive therapy | The Board of Trustees of the Leland Stanford Junior University | 29-Apr-14 | United States |
| 8,685,929 | Detecting CYP24 expression level as a marker for predisposition to cancer | The Regents of the University of California | 1-Apr-14 | United States |
| 8,685,387 | Simian E adenoviruses SAdV-39, -25.2, -26, -30, -37, and -38 | The Trustees of the University of Pennsylvania | 1-Apr-14 | United States |
| 8,686,016 | Schweinfurthins and uses thereof | The United States of America, as represented by the Secretary, Department of Health and Human Services | 1-Apr-14 | United States |
| 8,685,385 | Soft tissue and bone augmentation and bulking utilizing muscle-derived progenitor cells, compositions and treatments thereof | Univeristy of Pittsburgh--of the Commonwelath System of Higher Education | 1-Apr-14 | United States |
| 8,697,095 | Inhibition of replication of oncogenic herpesviruses | University of South Florida | 15-Apr-14 | United States |
| 8,685,946 | Sequence-specific inhibition of small RNA function | Universiy of Massachusetts | 1-Apr-14 | United States |
| FOOD OR EDIBLE MATERIAL | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,709,526 | Use of a high-oleic and high-tocol diet in combination with a non-tocol antioxidant for improving animal meat quality | E.I. duPont de Nemours and Company | 29-Apr-14 | United States |
| MULTICELLULAR LIVING ORGANISMS | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,692,051 | Methods for testing for caloric restriction (CR) mimetics | BioMarker Pharmaceuticals, Inc. | 8-Apr-14 | United States |
| 8,710,301 | Method for producing male sterile plants using plant beclin 1/ATG6 expression | Council of Scientific & Industrial Research | 29-Apr-14 | India |
| 8,692,072 | Plant transcription factors | E.I. du Pont de Nemours and Company | 8-Apr-14 | United States |
| 8,692,070 | Plants with improved nitrogen utilization and stress tolerance | Iowa Corn Promotion Board | 8-Apr-14 | United States |
| 8,697,949 | Temporal regulation of gene expression by MicroRNAs | Monsanto Technology LLC | 15-Apr-14 | United States |
| 8,692,068 | Promoter molecules for use in plants | Monsanto Technology LLC | 8-Apr-14 | United States |
| 8,692,071 | Drought responsive promoters HVA22e and PLDdelta identified from Arabidopsis thaliana | Monsanto Technology LLC | 8-Apr-14 | United States |
| 8,704,041 | Methods and compositions for targeted polynucleotide modification | Pioneer Hi Bred International Inc | 22-Apr-14 | United States |
| 8,692,052 | Genetically modified mice and engraftment | Regeneron Pharmaceuticals | 8-Apr-14 | United States |
| 8,692,053 | Soybean gene for resistance to alphis glycines | The Board of Trustees of the University of Illinois | 8-Apr-14 | United States |
| 8,686,224 | Plant defense signal peptides | Washington State University Research Foundation | 1-Apr-14 | United States |
| NATURAL RESINS OR DERIVATIVES | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,686,114 | Variant sucrose transporter polypeptides | E I du Pont de Nemours and Company | 1-Apr-14 | United States |
| 8,710,186 | Taste receptors of the T1R family from domestic cat | Monell Chemical Senses Center | 29-Apr-14 | United States |
| 8,710,191 | Antibodies to CCR2 | Pfizer Inc. | 29-Apr-14 | United States |
| 8,703,921 | Compositions and methods for delivering inhibitory oligonucleotides | The United States of America, as represented by the Secretary, Department of Health & Human Services | 22-Apr-14 | United States |
| 8,703,909 | Selective delivery of molecules into cells or marking of cells in diseased tissue regions using environmentally sensitive transmembrane peptide | Yale University | 22-Apr-14 | United States |
| ORGANIC COMPOUNDS | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,691,962 | Peroxidase gene nematode inducible promotors and methods of use | BASF Plant Science GmbH | 8-Apr-14 | Germany |
| 8,691,786 | Methods and compositions for the specific inhibition of gene expression by double-stranded RNA | City of Hope | 8-Apr-14 | United States |
| 8,703,930 | Cancer cell-specific apoptosis-inducing agents that target chromosome stabilization-associated genes | Genecare Research Institute Co., Ltd. | 22-Apr-14 | Japan |
| 8,710,209 | Modulation of HSP47 expression | Nitto Denko Corporation | 29-Apr-14 | Japan |
| 8,697,851 | MiRNA-regulated differentiation-dependent self-deleting cassette | Regeneron Pharmaceuticals, Inc. | 15-Apr-14 | United States |
| 8,697,853 | TAL effector-mediated DNA modification | Regents of the University of Minnesota | 15-Apr-14 | United States |
| 8,703,929 | Compositions comprising siRNA and plasmids | Senesco Technologies, Inc. | 22-Apr-14 | United States |
| 8,686,125 | Chimeric promoters comprising MYB10 repeat element and methods for regulating plant gene expression | The New Zealand Institute for Plant and Food Research Limited | 1-Apr-14 | New Zealand |
| 8,710,207 | Compositions, organisms, systems, and methods for expressing a gene product in plants using SCBV expression control sequences operable in monocots and dicots | The Texas A&M University Systems | 29-Apr-14 | United States |
| 8,691,966 | RNA containing modified nucleosides and methods of use thereof | The Trustees of the University of Pennsylvania | 8-Apr-14 | United States |
| RADIANT ENERGY | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,704,165 | Gene detecting methods without using PCR | Huang; Lequn | 22-Apr-14 | United States |
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