| MARCH, 2012 Gene-Related Patents Issued - Full patent | ||||
| CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,129,180 | Protein exhibiting activity of pyrethrin biosynthetic enzyme, gene encoding the protein, and vector bearing the gene | An Educational Foundation Kinki University | 6-Mar-12 | United States |
| 8,133,689 | Members of the capsaicin/vanilloid receptor family of proteins and uses thereof | Bayer Schering Pharma Aktiengesellschaft | 13-Mar-12 | Gerrmany |
| 8,129,176 | Integrated active flux microfluidic devices and methods | California Institute of Technology | 6-Mar-12 | United States |
| 8,129,110 | Probe, probe set, probe-immobilized carrier, and genetic testing method | Canon Kabushiki Kaisha | 6-Mar-12 | Japan |
| 8,129,109 | Probe, probe set, probe-immobilized carrier, and genetic testing method | Canon Kabushiki Kaisha | 6-Mar-12 | Japan |
| 8,129,108 | Probe, probe set, probe-immobilized carrier, and genetic testing method | Canon Kabushiki Kaisha | 6-Mar-12 | Japan |
| 8,133,668 | Probe, probe set, probe-immobilized carrier, and genetic testing method | Canon Kabushiki Kaisha | 13-Mar-12 | Japan |
| 8,137,953 | Lactic acid-producing yeast cells having nonfunctional L- or D-lactate:ferricytochrome C oxidoreductase cells | Cargill Inc. | 20-Mar-12 | United States |
| 8,137,911 | Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences | CellScript, Inc. | 20-Mar-12 | United States |
| 8,143,061 | Industrial method for producing RNA and system for carrying out said method | Centre National de la Recherche Scientifique | 27-Mar-12 | France |
| 8,137,918 | Sperm-specific cation channel, CatSper4, and uses therefor | Children's Medical Center Corporation | 20-Mar-12 | United States |
| 8,137,946 | Recombinant GRAS strains expressing thermophilic arabinose isomerase as an active form and method of preparing food grade tagatose by using the same | CJ Cheiljedang Corporation | 20-Mar-12 | Korea |
| 8,137,907 | Orthotopic and genetically tractable non-human animal model for liver cancer and the uses thereof | Cold Spring Harbor Laboratory | 20-Mar-12 | United States |
| 8,137,966 | Rat embryonic stem cell | Dainippon Sumitomo Pharma Co., Ltd. | 20-Mar-12 | Japan |
| 8,129,134 | Methods of cleaving DNA with rationally-designed meganucleases | Duke University | 6-Mar-12 | United States |
| 8,133,697 | Methods of cleaving DNA with rationally-designed meganucleases | Duke University | 13-Mar-12 | United States |
| 8,143,016 | Methods of cleaving DNA with rationally-designed meganucleases | Duke University | 27-Mar-12 | United States |
| 8,143,015 | Methods of cleaving DNA with rationally-designed meganucleases | Duke University | 27-Mar-12 | United States |
| 8,137,910 | Method of regulating gene expression | Duke University | 20-Mar-12 | United States |
| 8,142,994 | Classification, diagnosis and prognosis of acute myeloid leukemia by gene expression profiling | Erasmus University Medical Center Rotterdam | 27-Mar-12 | Netherlands |
| 8,143,032 | Alleles of the thrA gene of Enterobacteriaceae | Evonik Degussa GmbH | 27-Mar-12 | Gerrmany |
| 8,133,714 | Process for the fermentative preparation of organic chemical compounds using coryneform bacteria in which the SugR gene is present in attenuated form | Evonik Degussa GmbH | 13-Mar-12 | Gerrmany |
| 8,137,970 | Methods for inducing the differentiation of hematopoietic stem cells into megakaryocytes and platelets, and gene controlling the differentiation | Ewha University-Industry Collaboration Foundation | 20-Mar-12 | Korea |
| 8,143,003 | Method for detecting oral squamous-cell carcinoma | Fujifilm Corporation | 27-Mar-12 | Japan |
| 8,133,674 | Method of profiling gene expression in a subject having diabetes | GeneNews Corporation | 13-Mar-12 | United States |
| 8,133,675 | Method of profiling gene expression in a subject having an infectious disease | GeneNews Corporation | 13-Mar-12 | United States |
| 8,142,998 | Osteoarthritis biomarkers and uses thereof | GeneNews, Inc. | 27-Mar-12 | Canada |
| 8,129,154 | Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate | Genomatica, Inc. | 6-Mar-12 | United States |
| 8,137,963 | Method for highly amplifying target gene in mammalian cell and vector therefor | Hiroshima University | 20-Mar-12 | Japan |
| 8,143,008 | Method of nucleic acid amplification | Illumina, Inc. | 27-Mar-12 | United States |
| 8,137,916 | Susceptibility gene for alzheimer's disease | Isis Innovation Ltd. | 20-Mar-12 | United Kingdom |
| 8,129,163 | Gene suitable for alcohol dehydrogenase, vector and transformant | Kaneka Corporation | 6-Mar-12 | Japan |
| 8,129,144 | Papilloma pseudovirus and preparation | Loyola University Chicago | 6-Mar-12 | United States |
| 8,143,024 | Chlamydia trachomatis genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection | Merck Serono Biodevelopment | 27-Mar-12 | France |
| 8,129,119 | System for manipulating nucleic acids | Modular Genetics, Inc. | 6-Mar-12 | United States |
| 8,137,919 | Method of determining the sensitivity of cancer cells to EGFR inhibitors including cetuximab, panitumumab and erlotinib | Montefiore Medical Center | 20-Mar-12 | United States |
| 8,129,181 | F1B-TMIR plasmid vector and transgenic mouse | National Health Research Institutes | 6-Mar-12 | Taiwan |
| 8,143,007 | Nested primer sets for amplifying mouse immunoglobulin variable gene segments | National Institute of Immunology | 27-Mar-12 | India |
| 8,129,122 | Method of predicting metastasis of oral cavity cancer into cervical lymph node and diagnosis kit to be used in the prediction | National Institute of Radiological Sciences | 6-Mar-12 | Japan |
| 8,137,951 | Methods for producing hyaluronan in a recombinant host cell | Novozymes, Inc. | 20-Mar-12 | United States |
| 8,129,125 | Gene and protein expression profiles associated with the therapeutic efficacy of EGFR-TK inhibitors | Nuclea Biotechnologies, Inc. | 6-Mar-12 | United States |
| 8,129,112 | Polymorphisms in the human CYP2D6 gene promoter region and their use in diagnostic and therapeutic applications | PGxHealth, LLC | 6-Mar-12 | United States |
| 8,143,002 | Methods for isolating and characterizing endogenous mRNA-protein (mRNP) complexes | Ribonomics, Inc. | 27-Mar-12 | United States |
| 8,133,725 | Bone marrow stromal cells comprising a nucleic acid encoding a notch intracellular domain | SanBio, Inc. | 13-Mar-12 | United States |
| 8,137,933 | Mammalian expression vector pUHAB | Schering Corporation | 20-Mar-12 | United States |
| 8,129,120 | Methods for genetic analysis of DNA to detect sequence variances | Sequenom, Inc. | 6-Mar-12 | United States |
| 8,133,678 | COT102 insecticidal cotton | Syngenta Participations AG | 13-Mar-12 | Switzerland |
| 8,129,161 | Bardet-Biedl susceptibility gene and uses thereof | The University of Iowa Research Foundation | 6-Mar-12 | United States |
| 8,143,038 | Thermophilic micro-organisms for ethanol production | TMO Renewables Limited | 27-Mar-12 | United Kingdom |
| 8,137,962 | Compositions for treating cystic fibrosis | University of Florida Research Foundation | 20-Mar-12 | United States |
| 8,137,914 | Variants of alpha-fetoprotein coding and expression sequences | University of North Carolina at Chapel Hill | 20-Mar-12 | United States |
| 8,143,029 | Methods and means related to diseases | Valipharma | 27-Mar-12 | United Kingdom |
| 8,143,009 | Toxicity typing using liver stem cells | VistaGen, Inc. | 27-Mar-12 | United States |
| 8,137,947 | Viral vectors whose replication and, optionally, passenger gene are controlled by a gene switch activated by heat in the presence or absence of a small-molecule regulator | Voellmy; Richard | 20-Mar-12 | Switzerland |
| 8,133,679 | Methods of identifying agents that diminish cellular toxicity associated with an .alpha.-synuclein polypeptide of Parkinson's disease in yeast | Whitehead Institute for Biomedical Research | 13-Mar-12 | United States |
| COMBINATORIAL CHEMISTRY TECHNOLOGY | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,138,123 | Gene expressing analysis tool | Takeda Pharmaceutical Company Limited | 20-Mar-12 | Japan |
| DATA PROCESSING | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,135,545 | System and method for collecting data regarding broad-based neurotoxin-related gene mutation association | Iverson Genetic Diagnostics, Inc. | 13-Mar-12 | United States |
| 8,145,436 | Method and systems for identifying micro-RNA targets and synthesizing novel micro-RNAs and uses of the same | The Trustees of the University of Pennsylvania | 27-Mar-12 | United States |
| 8,131,475 | Methods for identifying, diagnosing, and predicting survival of lymphomas | The United States of America as represented by the Secretary, Department of Health and Human Services | 6-Mar-12 | United States |
| DRUG | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,133,873 | Recombinant chemokine-antigen vaccine | Cancer Institute, Chinese Academy of Medical Sciences | 13-Mar-12 | China P. Rep. |
| 8,129,402 | Screening molecules with anti-prion activity: kits, methods and screened molecules | Centre National de la Recherche Scientifique | 6-Mar-12 | France |
| 8,138,225 | Histone deacetylase inhibitors based on alpha-ketoepoxide compounds | Errant Gene Therapeutics, LLC | 20-Mar-12 | United States |
| 8,129,355 | Ketone ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation | 6-Mar-12 | United States |
| 8,142,770 | Drug comprising as the active ingredient proliferative vector containing survivin promoter | Kosai; Kenichiro | 27-Mar-12 | Japan |
| 8,137,676 | Genetically engineered equine influenza virus and uses thereof | Mount Sinai School of Medicine | 20-Mar-12 | United States |
| 8,129,354 | Treatment of neurological disorders by dsRNA administration | Novartis AG | 6-Mar-12 | Switzerland |
| 8,143,229 | Method for production of a transformed cell | Qiagen GmbH | 27-Mar-12 | Gerrmany |
| 8,143,232 | Gene fusion targeted therapy | The Regents of the University of Michigan | 27-Mar-12 | United States |
| 8,128,921 | Use of conditional plasmodium strains lacking nutrient transporters in malaria vaccination | University of Connecticut | 6-Mar-12 | United States |
| 8,137,662 | Proliferated cell lines and uses thereof | University of South Florida | 20-Mar-12 | United States |
| MULTICELLULAR LIVING ORGANISMS | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,134,046 | Method for producing arachidonic acid and/or eicosapentaenoic acid in useful transgenic plants | BASF Plant Science GmbH | 13-Mar-12 | Gerrmany |
| 8,143,479 | Plastidic phosphoglucomutase genes | E I du Pont de Nemours and Company | 27-Mar-12 | United States |
| 8,134,045 | Protein involved in restoration of cytoplasmic male sterility to fertility and gene encoding the protein and gene | Institut National de la Recherche Agronomique | 13-Mar-12 | France |
| 8,143,478 | Peptide transporting to chromoplasts in petals and method of constructing plant having yellowish petals by using the same | Kirin Beer Kabushiki Kaisha | 27-Mar-12 | Japan |
| 8,129,589 | Protoporphyrinogen oxidase having activity of imparting resistance against acifluorfen and gene thereof | Nippon Soda Co., Ltd. | 6-Mar-12 | Japan |
| 8,143,484 | Method for regulating agrobacterium-mediated transformation | Pioneer Hi-Bred International, Inc. | 27-Mar-12 | United States |
| 8,129,588 | Regulatory sequences for expressing gene products in plant reproductive tissue | Syngenta Participations AG | 6-Mar-12 | Switzerland |
| 8,134,047 | Maize plants with reduced gene silencing | The Regents of the University of California | 13-Mar-12 | United States |
| 8,138,391 | Or gene and its use in manipulating carotenoid content and composition in plants and other organisms | The United States of America as represented by the Secretary of Agriculture | 20-Mar-12 | United States |
| 8,143,480 | Compositions and methods for efficient gene silencing in plants | Whitehead Institute for Biomedical Research | 27-Mar-12 | United States |
| NATURAL RESINS OR DERIVATIVES | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,133,974 | Ferroportin1 nucleic acids, proteins, antibodies and methods | Children's Medical Center Corporation | 13-Mar-12 | United States |
| ORGANIC COMPOUNDS | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,143,390 | Compositions and methods for inhibiting expression of anti-apoptotic genes | Alnylam Pharmaceuticals, Inc. | 27-Mar-12 | United States |
| 8,129,519 | Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof | Cholody; Wieslaw M. | 6-Mar-12 | United States |
| 8,138,327 | Inducible systems and methods for controlling siRNA expression | City of Hope | 20-Mar-12 | United States |
| 8,138,329 | siRNA targeting connective tissue growth factor (CTGF) | Dharmacon, Inc. | 20-Mar-12 | United States |
| 8,143,413 | Polycationized phospholipid derivatives | Eisai R&D Management Co., Ltd. | 27-Mar-12 | Japan |
| 8,129,514 | Nucleotide sequences for regulating gene expression in plant trichomes and constructs and methods utilizing same | Evogene Ltd. | 6-Mar-12 | Israel |
| 8,133,985 | Peptide nucleic acids conjugated with multi-amine linkers and nucleic acid detecting device using the same | Panagene Inc. | 13-Mar-12 | Korea |
| 8,143,384 | Mutation of PRPS1 gene causing CMTX5 disease and the use thereof | Sungkyunkwan University Foundation for Corporate Collaboration | 27-Mar-12 | Korea |
| 8,129,510 | Minigene expression cassette | The Board of Trustees of the Leland Stanford Junior University | 6-Mar-12 | United States |
| 8,129,356 | Bmx mediated signal transduction in irradiated vascular endothelium | Vanderbilt University | 6-Mar-12 | United States |
| 8,138,324 | Expression system for proteins | Xbrane Bioscience AB | 20-Mar-12 | Sweden |
| PLANT PROTECTING AND REGULATING COMPOSITIONS | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,143,192 | Methods for increasing the resistance of plants to hypoxic conditions | Bayer Cropscience N.V. | 27-Mar-12 | Belgium |
| SURGERY | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,131,371 | Methods and apparatus for monopolar renal neuromodulation | Ardian, Inc. | 6-Mar-12 | United States |
| 8,145,317 | Methods for renal neuromodulation | Ardian, Inc. | 27-Mar-12 | United States |



