FEBRUARY, 2012 Gene-Related Patents Issued - Full patent
CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY
Pat No Title Assignee Date Issued Country
8,114,639 Method for producing an L-amino acid using a bacterium of the enterobacteriaceae family with attenuated expression of the sfmACDFH-fimZ cluster or the fimZ gene Ajinomoto Co., Inc. 14-Feb-12 Japan
8,114,649 L-cysteine producing microorganism and a method for producing L-cysteine Ajinomoto Co., Inc. 14-Feb-12 Japan
8,114,632 Method of producing biologically active polypeptide having insulinotropic activity Biocon Limited 14-Feb-12 India
8,124,351 Quantification of fusion proteins and their activity from chromosomal translocation Board of Regents, The University of Texas System 28-Feb-12 United States
8,119,351 CC2D2A gene mutations associated with Joubert syndrome and diagnostic methods for identifying the same Centre for Addiction and Mental Health 21-Feb-12 Canada
8,114,650 Nucleic acid and its use effecting ciliate tetrahymena bifunctional dihydrofolate reductase-thymidylate synthase deficiency Cilian AG 14-Feb-12 Germany
8,124,369 Method of cleaving DNA with rationally-designed meganucleases Duke University 28-Feb-12 United States
8,119,361 Methods of cleaving DNA with rationally-designed meganucleases Duke University 21-Feb-12 United States
8,119,381 Rationally-designed meganucleases with altered sequence specificity and DNA-binding affinity Duke University 21-Feb-12 United States
8,114,597 Method of profiling gene expression in a subject undergoing a treatment GeneNews Corporation 14-Feb-12 United States
8,110,358 Method of profiling gene expression in a subject having prostate cancer GeneNews Corporation 7-Feb-12 United States
8,114,624 Use of the ornithine transcarbamylase (OTC), as a marker for diagnosing brain damages Genoscreen 14-Feb-12 France
8,110,363 Expression profiles to predict relapse of prostate cancer Illumina, Inc. 7-Feb-12 United States
8,114,596 Producing, cataloging and classifying sequence tags Kaufman; Joseph C. 14-Feb-12 United States
RE43,166 Gene encoding chondroitinase ABC and uses therefor Maruha Nichiro Foods, Inc. 7-Feb-12 Japan
8,119,377 Recombinant microorganisms for increased production of organic acids Michigan Biotechnology Institute 21-Feb-12 United States
8,110,362 Method for determining a tongue cancer Niigata University 7-Feb-12 Japan
8,124,341 Genes and polypeptides relating to hepatocellular or colorectal carcinoma Oncotherapy Science, Inc. 28-Feb-12 Japan
8,124,345 Cystic fibrosis transmembrane conductance regulator gene mutations Quest Diagnostics Investments Incorporated 28-Feb-12 United States
8,114,583 Switch-region: target and method for inhibition of bacterial RNA polymerase Rutgers, The State University of New Jersey 14-Feb-12 United States
8,114,620 Diagnostic and therapeutic target PRKX proteins for neurodegenerative diseases Takeda Pharmaceutical Company Limited 14-Feb-12 Japan
8,119,340 Methods and compositions for diagnosis and treatment of B cell chronic lymphocytic leukemia The Feinstein Institute for Medical Research 21-Feb-12 United States
8,119,341 Genetic variant of the annexin A5 gene Universitaesklinikum Muenster 21-Feb-12 Germany
8,114,593 Cancer biomarker genes and gene products and methods for using the same University of Medicine and Dentistry of New Jersey 14-Feb-12 United States
DATA PROCESSING
Pat No Title Assignee Date Issued Country
8,112,230 Method of network-based identification of multicomponent synergy and compositions for use as effective component of anti-angiogenesis medicines Tsinghua University 7-Feb-12 China P. Rep.
DRUG
Pat No Title Assignee Date Issued Country
8,114,851 Method and medicament for inhibiting the expression of a given gene Alnylam Pharmaceuticals, Inc. 14-Feb-12 United States
8,119,590 Prevention and treatment of restenosis by local administration of drug Cedars-Sinai Medical Center 21-Feb-12 United States
8,110,187 Purification and characterization of cytotoxic lymphocyte maturation factor and monoclonal antibodies thereto Hoffman-La Roche Inc. 7-Feb-12 United States
8,124,093 Human cytomegalovirus neutralizing antibodies and use thereof Institute for Research in Biomedicine 28-Feb-12 Switzerland
8,119,146 Expressing hepatitis B virus surface antigen for vaccine preparation Medina-Selby; Angelica 21-Feb-12 United States
8,119,136 Methods of modulating apoptosis by administration of relaxin agonists or antagonists Molecular Medicine Research Institute 21-Feb-12 United States
8,124,101 Genetically engineered swine influenza virus and uses thereof Mount Sinai School of Medicine 28-Feb-12 United States
8,110,183 Method for sustained expression of an exogenous gene National Tsing Hua University 7-Feb-12 Taiwan
8,114,401 Chlamydia trachomatis antigens Ratti; Giulio 14-Feb-12 Italy
8,114,395 Treatment of viral diseases with recombinant interferon .alpha. Sichuan Biotechnology Research Center 14-Feb-12 China P. Rep.
8,110,560 Spinal muscular atrophy (SMA) treatment via targeting of SMN2 splice site inhibitory sequences University of Massachusetts 7-Feb-12 United States
8,110,556 Method of expressing human lysosomal protein in brain cells University of Medicine and Dentistry of New Jersey 7-Feb-12 United States
8,119,589 Modulation of CD4.sup.+ T cell responses by a tick saliva protein, Salp15 and polypeptides derived therefrom University of North Carolina at Charlotte 21-Feb-12 United States
MULTICELLULAR LIVING ORGANISMS
Pat No Title Assignee Date Issued Country
8,115,087 Wheat with altered branching enzyme activity and starch and starch containing products derived therefrom Commonwealth Scientific and Industrial Research Organisation 14-Feb-12 Australia
8,124,843 Methods and genetic compositions to limit outcrossing and undesired gene flow in crop plants Dow AgroSciences LLC 28-Feb-12 United States
8,124,831 Transgenic mice carrying functional single nucleotide polymorphisms in brain-specific tryptophan hydroxylase Duke University 28-Feb-12 United States
8,115,055 Down-regulation of gene expression using artificial microRNAs E.I. du Pont de Nemours and Company 14-Feb-12 United States
8,119,855 Resistance to abiotic stress in plants Expressive Research B.V. 28-Feb-12 Netherlands
8,110,722 Aromatic acyltransferase genes Local Independent Administrative Institution Aomori Prefectural Industrial Technology Research Center 7-Feb-12 Japan
8,124,835 Acyl-coa-dependent diacylglycerol acyltransferas 1 (DGAT1) gene from Tropaeolum majus, protein encoded thereby and uses thereof National Research Council of Canada 28-Feb-12 Canada
8,110,719 ABI1 conditional knockout mouse New York Blood Center, Inc. 7-Feb-12 United States
8,124,834 Use of active cytokinin synthase gene Riken 28-Feb-12 Japan
8,115,058 Rice promoters for regulation of plant expression Syngenta Participations AG 14-Feb-12 Switzerland
8,124,837 Engineering resistance to Pierce's disease by expression of a Xyella fastidiosa HecA-like hemagglutinin protein The Regents of the University of California 28-Feb-12 United States
8,115,059 Gene expression modulation system for use in plants and method for modulating gene expression in plants University of Kentucky Research Foundation 14-Feb-12 United States
NATURAL RESINS OR DERIVATIVES
Pat No Title Assignee Date Issued Country
8,124,741 Antibodies to tumor associated proteins Agensys, Inc. 28-Feb-12 United States
8,110,662 Antibody directed to protein involved in maintaining differentiation of smooth muscle cells Chugai Seiyaku Kabushiki Kaisha 7-Feb-12 Japan
8,124,728 CA125 gene and its use for diagnostic and therapeutic interventions The Board of Trustees of the University of Arkansas 28-Feb-12 United States
ORGANIC COMPOUNDS
Pat No Title Assignee Date Issued Country
8,114,982 Multi-microRNA methods and compositions Albert Einstein College of Medicine of Yeshiva University 14-Feb-12 United States
8,119,608 Method and medicament for inhibiting the expression of a given gene Alnylam Pharmaceuticals, Inc. 21-Feb-12 United States
8,114,984 RNAi modulation of Aha and therapeutic uses thereof Alnylam Pharmaceuticals, Inc. 14-Feb-12 United States
8,114,981 Method and medicament for inhibiting the expression of a given gene Alnylam Pharmaceuticals, Inc. 14-Feb-12 United States
8,124,752 Compositions and methods for inhibiting expression of the MYC gene Alnylam Pharmaceuticals, Inc. 28-Feb-12 United States
8,124,748 Cell surface glycoprotein Ares Trading S.A. 28-Feb-12 Switzerland
8,119,785 Nucleic acid sequences and homologous recombination vectors for distruption of a Fel D I gene Avner; David B. 21-Feb-12 United States
8,119,791 si-RNA-mediated gene silencing technology to inhibit tyrosinase and reduce pigmentation Avon Products, Inc. 21-Feb-12 United States
8,110,668 Sperm-specific cation channel, catsper-3 and uses therefor Children's Medical Center Corporation 7-Feb-12 United States
8,110,672 Promoter engineering and genetic control Massachusetts Institute of Technology 7-Feb-12 United States
8,124,755 hTERT gene expression regulatory gene National University Corporation Tottori University 28-Feb-12 Japan
8,119,610 Method for efficient RNA interference in mammalian cells The Regents of the University of California 21-Feb-12 United States
8,124,753 Compositions and methods for inhibiting translation of a Mect1-MAML2 chimeric gene The United States of America as represented by the Department of Health and Human Services 28-Feb-12 United States
8,114,976 Cryptosporidium hominis genes and gene products for chemotherapeutic, immunoprophylactic and diagnostic applications Virginia Commonwealth University 14-Feb-12 United States
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