| DECEMBER, 2012 Gene-Related Patents Issued - Full patent: http://patft.uspto.gov/netahtml/PTO/srchnum.htm | ||||
| ANIMAL HUSBANDRY | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,327,803 | Method for processing a large number of fish eggs | Hashimoto Electronic Industry Co., Ltd. | 11-Dec-12 | Japan |
| CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,338,162 | Obligately anaerobic mutant lactic acid bacterium and preparation method therefor, and expression vector functioning in obligately anaerobic lactic acid bacterium | Anaeropharma Science, Inc. | 25-Dec-12 | Japan |
| 8,323,897 | Multiplex amplification of polynucleotides | Applied Biosystems, LLC | 4-Dec-12 | United States |
| 8,323,952 | Alcoholic xylose fermentation at high temperatures by the thermotolerant yeast Hansenula polymorpha | Archer Daniels Midland Company | 4-Dec-12 | United States |
| 8,329,448 | Yeast host, transformant and method for producing heterologous proteins | Asahi Glass Company, Limited | 11-Dec-12 | United States |
| 8,334,137 | MN gene and protein | Bayer Healthcare LLC | 18-Dec-12 | United States |
| 8,338,179 | Neomycin-phosphotransferase-genes and methods for the selection of recombinant cells producing high levels of a desired gene product | Boehringer Ingelheim Pharma GmbH & Co. KG | 25-Dec-12 | Germany |
| 8,329,434 | Enhanced promoter and method for producing L-lysine using the same | CJ Cheiljedang Corporation | 11-Dec-12 | Korea |
| 8,323,935 | Optimized strains of Yarrowia lipolytica for high eicosapentaenoic acid production | E I du Pont de Nemours and Company | 4-Dec-12 | United States |
| 8,323,960 | Ammonium transporter promoters for gene expression in oleaginous yeast | E I du Pont de Nemours and Company | 4-Dec-12 | United States |
| 8,334,126 | Coryneform host-vector systems comprising a chromosomal ALR gene which is attenuated or eliminated and methods of using | Evonik Degussa GmbH | 18-Dec-12 | Germany |
| 8,329,398 | Universal amplification of fragmented RNA | Genomic Health, Inc. | 11-Dec-12 | United States |
| 8,329,420 | Screening method for a substance that binds to an intracellular region of TLR4 | Hiroshima University | 11-Dec-12 | Japan |
| 8,334,129 | Microorganism capable of producing polyhydroxyalkanoate, polyhydroxyalkanoate synthase, and gene encoding the same | Hitachi Chemical Co., Ltd. | 18-Dec-12 | Japan |
| 8,329,429 | Method of enhancing recombinant protein production | Induce Biologics Inc. | 11-Dec-12 | United States |
| 8,338,168 | Chimeric glycoproteins and pseudotyped lentiviral vectors | Institut National de la Sante et de la Recherche Medicale | 25-Dec-12 | France |
| 8,329,430 | Polymyxin synthetase and gene cluster thereof | Korea Research Institute of Bioscience and Biotechnology | 11-Dec-12 | Korea |
| 8,323,926 | Gene from Hancenula polymorpha capable of controlling unfolded protein response and method for increasing effect of secretion using the same | Korea Research Institute of Bioscience and Biotechnology | 4-Dec-12 | Korea |
| 8,329,463 | RNA interference mediating small RNA molecules | Max-Planck-Gesellschaft zur Forderung der Wissenschaften E.V. | 11-Dec-12 | Germany |
| 8,334,111 | Human diacylglycerol acyltransferase 2 (DGAT2) family members and uses therefor | Millennium Pharmaceuticals, Inc. | 18-Dec-12 | United States |
| 8,329,472 | Gene associated with foam formation in acetic acid bacterium, acetic acid bacterium modified to reduce foam formation, and a method for producing vinegar by culturing an acetic acid bacterium modified to reduce foam formation | Mizkan Group Corporation | 11-Dec-12 | Japan |
| 8,334,139 | Plasmids for transforming plant cells | Monsanto Technology LLC | 18-Dec-12 | United States |
| 8,323,898 | Method for identifying pathogenic microorganisms responsible for infection by extracting the DNA of a microorganism | National University Corporation University of Toyama | 4-Dec-12 | Japan |
| 8,329,426 | High throughput method for measuring total fermentables in small amount of plant part | Pioneer Hi-Bred International, Inc. | 11-Dec-12 | United States |
| 8,329,462 | Methods and compositions relating to improved lentiviral vectors and their applications | Research Development Foundation | 11-Dec-12 | United States |
| 8,338,107 | Method for producing polymers having a preselected activity | Scripps Research Institute | 25-Dec-12 | United States |
| 8,338,099 | Reference genes for the normalization of gene expression analysis data | SIRS-Lab GmbH | 25-Dec-12 | Germany |
| 8,323,893 | Administration of exogenous miRNA or siRNA | Sloan-Kettering Institute for Cancer Research | 4-Dec-12 | United States |
| 8,323,896 | Epidermal growth factor (EGF) expression and/or polymorphisms thereof for predicting the risk of developing cancer | The General Hospital Corporation | 4-Dec-12 | United States |
| 8,338,138 | Methods for making and using molecular switches involving circular permutation | The John Hopkins University | 25-Dec-12 | United States |
| 8,334,124 | Modified Aspergillus niger phytase | The United States of America as represented by the Secretary of Agriculture | 18-Dec-12 | United States |
| 8,334,101 | Intracellular DNA receptor | University of Massachusetts | 18-Dec-12 | United States |
| 8,323,963 | Construction and use of genes encoding pathogenic epitopes for treatment of autoimmune disease | University of Southern California | 4-Dec-12 | United States |
| 8,334,096 | Methods and compositions related to arrhythmogenic right ventricular cardiomyopathy (ARVC) | Washington State University Research Foundation | 18-Dec-12 | United States |
| 8,338,098 | Methods and compositions for improved cattle longevity and milk production | Wisconsin Alumni Research Foundation | 25-Dec-12 | United States |
| 8,338,147 | Process for producing D-mannitol | zuChem, Inc. | 25-Dec-12 | United States |
| DATA PROCESSING | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,332,159 | Method for enhancing efficacy of preparation of monoclonal antibody | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | 11-Dec-12 | Japan |
| 8,326,547 | Method of sequence optimization for improved recombinant protein expression using a particle swarm optimization algorithm | Nanjingjinsirui Science & Technology Biology Corp. | 4-Dec-12 | China P. Rep. |
| 8,332,157 | Information processing apparatus, information processing method, and program | Sony Corporation | 11-Dec-12 | Japan |
| DRUG | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,334,273 | Compositions and methods for inhibiting expression of factor VII gene | Alnylam Pharmaceuticals, Inc. | 18-Dec-12 | United States |
| 8,329,636 | Carcinoma diagnosis and treatment, based on ODC1 genotype | Arizona Board of Regents on Behalf of University of Arizona | 11-Dec-12 | United States |
| 8,334,271 | Use of VEGF in the treatment of retarded fetal growth in pregnancy | Ark Therapeutics, Ltd. | 18-Dec-12 | United Kingdom |
| 8,329,162 | Targeted gene delivery for dendritic cell vaccination | California Institute of Technology | 11-Dec-12 | United States |
| 8,329,641 | Remedies for ischemic disease of the limbs comprising administration of G-CSF | Chugai Seiyaku Kabushiki Kaisha | 11-Dec-12 | Japan |
| 8,338,474 | Use of phthalimide and/or sulphonamide derivatives in the treatment of diseases which require reducing the TNF-.alpha. levels and an exogenous source of nitric oxide, phthalimide derivatives, sulphonamide derivatives, and a method for obtaining a sulphonamide derivative | Dos Santos; Jean Leandro | 25-Dec-12 | Brazil |
| 8,323,659 | Method for diagnosing and/or treating tumor | Keio University | 4-Dec-12 | Japan |
| 8,329,670 | System for delivering nucleic acids for suppressing target gene expression by utilizing endogenous chylomicron | National University Corporation Tokyo Medical and Dental University | 11-Dec-12 | Japan |
| 8,334,272 | Methods for nucleic acid transfer into cells | Northwestern University | 18-Dec-12 | United States |
| 8,337,812 | Regulator of ephrin-Eph receptor signaling and mouse having abnormal ephrin-Eph receptor signaling mechanisms | RIKEN | 25-Dec-12 | Japan |
| 8,338,366 | Bioactive FUS1 peptides and nanoparticle-polypeptide complexes | The Board of Regents of the University of the Texas System | 25-Dec-12 | United States |
| 8,334,275 | Cellular genes regulated by HIV-1 infection and methods of use thereof | The Children's Hospital of Philadelphia | 18-Dec-12 | United States |
| 8,329,177 | Method of treating hypertrophic cardiomyopathy | The John Hopkins University | 11-Dec-12 | United States |
| 8,323,664 | Live vaccine strains of Francisella | The Secretary of State for Defence | 4-Dec-12 | United Kingdom |
| 8,337,831 | Live, oral vaccine for protection against Shigella dysenteriae serotype 1 | The United States of America, as Represented by the Secrectary, Department of Health and Human Services | 25-Dec-12 | United States |
| 8,323,706 | Antiestrogenic glyceollins suppress human breast and ovarian carcinoma proliferation and tumorigenesis | The United States of America, as represented by the Secretary of Agriculture | 4-Dec-12 | United States |
| 8,338,386 | Prevention/treatment of ichthyosis vulgaris, atopy and other disorders | University Court of the University of Dundee | 25-Dec-12 | United Kingdom |
| 8,323,618 | Ultrasmall superparamagnetic iron oxide nanoparticles and uses thereof | University of Houston System | 4-Dec-12 | United States |
| 8,329,681 | Methods and compositions for the efficient delivery of therapeutic agents to cells and animals | University of Massachusetts | 11-Dec-12 | United States |
| 8,334,274 | Immunomodulation of inflammatory conditions utilizing Follistatin-like Protein-1 and agents that bind thereto | University Of Pittsburg--Of The Commonwealth of Higher Education | 18-Dec-12 | United States |
| 8,337,829 | Conditioned medium and proliferated cell lines produced therefrom | University of South Florida | 25-Dec-12 | United States |
| 8,324,148 | Compositions for importing biologically active molecules into cells | Vanderbilt University | 4-Dec-12 | United States |
| 8,338,385 | Hybrid hepatocyte growth factor gene having high expression efficiency of two heterotypes of hepatocyte growth factor | ViroMed Co., Ltd. | 25-Dec-12 | Korea |
| 8,338,456 | Cut-point in PTEN protein expression that accurately identifies tumors and is predictive of drug response to a pan-ErbB inhibitor | Wyeth LLC | 25-Dec-12 | United States |
| MULTICELLULAR LIVING ORGANISMS | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,329,995 | Soybeans with reduced isoflavones | Arcadia Biosciences, Inc. | 11-Dec-12 | United States |
| 8,329,988 | Method for increasing pathogen resistance in transgenic plants | BASF Plant Science GmbH | 11-Dec-12 | Germany |
| 8,330,006 | Maize with good digestibility and disease resistant | Biogemma | 11-Dec-12 | France |
| 8,324,456 | Method for improving transformation efficiency using powder | Japan Tobacco Inc. | 4-Dec-12 | Japan |
| 8,338,664 | Nucleic acid molecules encoding plant proteins in the C3HC4 family and methods for the alteration of plant cellulose and lignin content | Monsanto Do Brasil LTDA. | 25-Dec-12 | Brazil |
| 8,329,990 | Crop grain filling gene GIF1 and the applications thereof | Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences | 11-Dec-12 | China P. Rep. |
| 8,334,427 | Induction of Xa27 by the avrXa27 gene in rice confers broad-spectrum resistance to Xanthomonas oryzae pv. oryzae and enhanced resistance to Xanthomonas oryzae pv. oryzicola | Temasek Life Sciences Laboratory | 18-Dec-12 | Singapore |
| ORGANIC COMPOUNDS | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,324,368 | GNAQ targeted dsRNA compositions and methods for inhibiting expression | Alnylam Pharmaceuticals, Inc. | 4-Dec-12 | United States |
| 8,334,373 | Nuclease resistant double-stranded ribonucleic acid | Alnylam Pharmaceuticals, Inc. | 18-Dec-12 | United States |
| 8,324,366 | Compositions and methods for delivering RNAI using lipoproteins | Alnylam Pharmaceuticals, Inc. | 4-Dec-12 | United States |
| 8,324,181 | Modulation of gene expression by oligomers targeted to chromosomal DNA | Board of Regents, The University of Texas System | 4-Dec-12 | United States |
| 8,329,882 | Genetic control of mammalian cells with synthetic RNA regulatory systems | California Institute of Technology | 11-Dec-12 | United States |
| 8,334,374 | Methods and means for obtaining modified phenotypes | Commonwealth Scientific and Industrial Research Organisation | 18-Dec-12 | Australia |
| 8,324,365 | Conjugate for gene transfer comprising oligonucleotide and hydrophilic polymer, polyelectrolyte complex micelles formed from the conjugate, and methods for preparation thereof | Korea Advanced Institute of Science and Technology | 4-Dec-12 | Korea |
| 8,324,363 | Microarray for detection of the deletion of exon 3 of the G-CSF gene | Lee; Sang Yup | 4-Dec-12 | Korea |
| 8,324,367 | Compositions and methods for making therapies delivered by viral vectors reversible for safety and allele-specificity | Medtronic, Inc. | 4-Dec-12 | United States |
| 8,338,578 | Cystic fibrosis gene mutations | Quest Diagnostics Investments Incorporated | 25-Dec-12 | United States |
| 8,329,888 | Small internally segmented interfering RNA | Santaris Pharma A/S | 11-Dec-12 | Denmark |
| 8,329,889 | In vivo gene sensors | Trustees of Boston University | 11-Dec-12 | United States |
| 8,329,892 | Methods and compositions for enhancing the efficacy and specificity of RNA silencing | University of Massachusetts | 11-Dec-12 | United States |
| 8,338,643 | Reagent for introduction of protein or gene | Waseda University | 25-Dec-12 | Japan |
| SURGERY | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,326,416 | Apparatus and method for delivering electrical signals to modify gene expression in cardiac tissue | Impulse Dynamics NV | 4-Dec-12 | Netherlands |



