| APRIL 2012 Gene-Related Patents Issued - Full patent | ||||
| CHEMISTRY: MOLECULAR BIOLOGY AND MICROBIOLOGY | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,153,431 | Compositions and methods for making mutations in cell lines and animals | ABT Holding Company | 10-Apr-12 | United States |
| 8,158,352 | Screening of a novel hepatic syndrome and its uses | Assistance Publique-Hopitaux de Paris | 17-Apr-12 | France |
| 8,158,595 | Modular aptamer-regulated ribozymes | California Institute of Technology | 17-Apr-12 | United States |
| 8,148,073 | Probe, probe set, probe-immobilized carrier, and genetic testing method | Canon Kabushiki Kaisha | 3-Apr-12 | Japan |
| 8,158,350 | Probe, probe set, probe-immobilized carrier, and genetic testing method | Canon Kabushiki Kaisha | 17-Apr-12 | Japan |
| 8,148,063 | Probe, probe set, probe-immobilized carrier, and genetic testing method | Canon Kabushiki Kaisha | 3-Apr-12 | Japan |
| 8,163,483 | Compositions and methods for spinocerebellar ataxia | Cedars-Sinai Medical Center | 24-Apr-12 | United States |
| 8,158,416 | CDNA corresponding to the antigenome of nonsegmented negative strand RNA viruses, and process for the production of such viruses encoding additional antigenically active proteins | Crucell Switzerland AG | 17-Apr-12 | Switzerland |
| 8,158,362 | Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype | deCODE Genetics ehf. | 17-Apr-12 | Island |
| 8,158,391 | Production of an .alpha.-carboxyl-.omega.-hydroxy fatty acid using a genetically modified Candida strain | DNA Twopointo, Inc. | 17-Apr-12 | United States |
| 8,148,098 | Methods of cleaving DNA with rationally-designed meganucleases | Duke University | 3-Apr-12 | United States |
| 8,163,514 | Methods of cleaving DNA with rationally-designed meganucleases | Duke University | 24-Apr-12 | United States |
| 8,163,521 | Self-assembled proteins and related methods and protein structures | Duquesne University of the Holy Ghost | 24-Apr-12 | United States |
| 8,153,404 | Alleles of the zwf gene from coryneform bacteria | Evonik Degussa GmbH | 10-Apr-12 | Germany |
| 8,163,492 | Microfluidic device and methods of using same | Fluidign Corporation | 24-Apr-12 | United States |
| 8,148,072 | Method of profiling gene expression in a subject having heart failure | GeneNews Corporation | 3-Apr-12 | United States |
| 8,148,076 | Gene expression profiling of EGFR positive cancer | Genomic Health, Inc. | 3-Apr-12 | United States |
| 8,158,384 | Methods for reducing or eliminating .alpha.-mannosidase resistant glycans in the production of glycoproteins | Glycofi, Inc. | 17-Apr-12 | United States |
| 8,148,136 | Diagnostics and vaccines for mycobacterial infections of animals and humans | HAV Vaccines Limited | 3-Apr-12 | United Kingdom |
| 8,153,433 | Mammalian cell lines for increasing longevity and protein yield from a cell culture | Immunomedics, Inc. | 10-Apr-12 | United States |
| 8,153,413 | High alkaline protease and use thereof | Japan Agency for Marine-Earth Science and Technology | 10-Apr-12 | Japan |
| 8,153,362 | Mitochondrial function of prohibitin 2 (PHB2) | Jichi Medical University | 10-Apr-12 | Japan |
| 8,163,525 | Method of expressing long-chain prenyl diphosphate synthase | Kaneka Corporation | 24-Apr-12 | Japan |
| 8,163,482 | BBS10 related diagnostic methods for Bardet-Biedl syndrome | Katsanis; Nicholas | 24-Apr-12 | United States |
| 8,148,137 | Mutant microorganism having improved production ability of branched amino acid and method for preparing branched amino acid using the same | Korea Advanced Institute of Science & Technology | 3-Apr-12 | Korea |
| 8,148,143 | Method and composition for genetically modifying non-human cells and animals | Kwang-Hua Development and Investment Ltd. | 3-Apr-12 | Hong Kong |
| 8,163,553 | Human trophoblast stem cells and use thereof | Lee; Jau-Nan | 24-Apr-12 | Taiwan |
| 8,163,473 | Method for using DNA repair capacity as a biomarker of breast cancer risk in women | Matta Murias; Jaime L. | 24-Apr-12 | France |
| 8,153,402 | Emulsion compositions | Medical Research Council | 10-Apr-12 | United Kingdom |
| 8,163,506 | Use of toll-like receptor-expressing cells | Meiji Co., Ltd. | 24-Apr-12 | Japan |
| 8,148,119 | Hydroxylase gene and use thereof | Microbiopharm Japan Co., Ltd. | 3-Apr-12 | Japan |
| 8,153,364 | Emulsion compositions | MRC | 10-Apr-12 | United Kingdom |
| 8,148,144 | pCryptoRNAi | National University Corporation Chiba University | 3-Apr-12 | Japan |
| 8,153,358 | Selection and enrichment of proteins using in vitro compartmentalization | New England Biolabs, Inc. | 10-Apr-12 | United States |
| 8,158,360 | Effects of inhibitors of FGFR3 on gene transcription | Novartis AG | 17-Apr-12 | Switzerland |
| 8,163,524 | Comparative analysis of extracellular RNA species | OncoMedx, Inc. | 24-Apr-12 | United States |
| 8,148,080 | Gene and protein relating to hepatocellular carcinoma and methods of use thereof | Oncotherapy Science, Inc. | 3-Apr-12 | Japan |
| 8,158,361 | Tumor marker | Qiagen GmbH | 17-Apr-12 | Germany |
| 8,153,385 | Target protein and target gene in drug designing and screening method | Reverse Proteomics Research Institute Co., Ltd | 10-Apr-12 | Japan |
| 8,158,351 | Method for determining inflammatory disease | Riken | 17-Apr-12 | Japan |
| 8,153,399 | Methods and compositions for inactivating glutamine synthetase gene expression | Sangamo Biosciences, Inc. | 10-Apr-12 | United States |
| 8,163,478 | Fertility restoration for Ogura cytoplasmic male sterile Brassica and method | Syngenta Participations AG | 24-Apr-12 | Switzerland |
| 8,158,355 | Method to generate or determine nucleic acid tags corresponding to the terminal ends of DNA molecules using sequences analysis of gene expression (terminal SAGE) | The Agency For Science, Technology and Research | 17-Apr-12 | Singapore |
| 8,153,372 | Method for simultaneously determining in a single multiplex reaction gender of donors and quantities of genomic DNA and ratios thereof, presence and extent of DNA degradation, and PCR inhibition within a human DNA sample | The Board of Regents for Oklahoma State University | 10-Apr-12 | United States |
| 8,163,476 | CUDR as biomarker for cancer progression and therapeutic response | The Chinese University of Hong Kong | 24-Apr-12 | China P. Rep. |
| 8,163,505 | Methods using PBK1 for identifying agents that treat metabolic disorders | The Penn State Research Foundation | 24-Apr-12 | United States |
| 8,148,124 | Regulation of gene expression by protein methylation | The Regents of the University of California | 3-Apr-12 | United States |
| 8,148,129 | Generation of potent dominant negative transcriptional inhibitors | The Regents of the University of California | 3-Apr-12 | United States |
| 8,148,060 | Recombinant viral vector for gene transfer into lymphoid cells | The Research Foudation for Microbial Diseases of Osaka University | 3-Apr-12 | Japan |
| 8,153,376 | Means and methods for diagnosing and/or treating a subject at risk of developing heart failure | Universiteit Maastricht | 10-Apr-12 | United States |
| 8,153,366 | Methods and compositions for predicting drug responses | University of Washington | 10-Apr-12 | United States |
| 8,148,102 | Sequences for FK228 biosynthesis and methods of synthesizing FK228 and FK228 analogs | UWM Research Foundation, Inc. | 3-Apr-12 | United States |
| 8,153,368 | Four-jointed box (FJX1) in cancer diagnosis and treatment | Vanderbilt University | 10-Apr-12 | United States |
| 8,153,403 | Process for identifying existence of single nucleotide polymorphism without DNA sequencing | Zainiev; Gafur | 10-Apr-12 | United States |
| DATA PROCESSING | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,160,854 | Method of managing and displaying gene expression data | Hitachi Software Engineering Co., Ltd. | 17-Apr-12 | Japan |
| 8,150,625 | System and method for classifying a body tissue sample | Yissum Research Development Company of the Hebrew University of Jerusalem | 3-Apr-12 | Israel |
| DRUG | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,148,344 | Compositions and methods for mediating RNAi in vivo | Alnylam Pharmaceuticals, Inc. | 3-Apr-12 | United States |
| 8,163,711 | Compositions and methods for inhibiting expression of the HAMP gene | Alnylam Pharmaceuticals, Inc. | 24-Apr-12 | United States |
| 8,163,280 | Antibodies to c-Met | Amgen Fremont Inc | 24-Apr-12 | United States |
| 8,147,820 | Attenuated vaccine against fish pathogen Francisella sp | Board of Supervisors of Louisiana State University And Agricultural and Mechanical College | 3-Apr-12 | United States |
| 8,147,827 | Tumor treatment | Genentech, Inc. | 3-Apr-12 | United States |
| 8,148,345 | Composition and method for in vivo and in vitro attenuation of gene expression using double stranded RNA | Georgia Health Sciences University Research Institute, Inc. | 3-Apr-12 | United States |
| 8,153,138 | Recombinant MVA virus | GSF-Forschungszentrum fur Umwelt und Gesundheit GmbH | 10-Apr-12 | Germany |
| 8,158,600 | Methods and compositions for detecting and treating retinal diseases based on metargidin (ADAM-15) | Inana; George | 17-Apr-12 | United States |
| 8,148,343 | Tumor suppressor factor | Molecular Discovery Systems | 3-Apr-12 | Australia |
| 8,148,342 | Oligoribonucleotides and methods of use thereof for treatment of alopecia, acute renal failure and other diseases | Quark Pharmaceuticals Inc. | 3-Apr-12 | United States |
| 8,158,596 | Materials and methods for FOXP3 tumor suppression | The Regents of the University of Michigan | 17-Apr-12 | United States |
| 8,147,823 | Method of treating or retarding the development of blindness | The Trustees of the University of Pennsylvania | 3-Apr-12 | United States |
| 8,147,803 | Ultrasmall superparamagnetic iron oxide nanoparticles and uses thereof | The University of Houston | 3-Apr-12 | United States |
| 8,153,110 | Environment-responding siRNA carrier using disulfide-cross-linked polymeric micelle | The University of Tokyo | 10-Apr-12 | Japan |
| 8,153,116 | Use of conditional plasmodium strains lacking an essential gene in malaria vaccination | University of Connecticut | 10-Apr-12 | United States |
| 8,153,155 | Arginine-conjugated bioreducible poly(disulfide amine) polymers for gene delivery system | University of Utah | 10-Apr-12 | United States |
| 8,153,154 | Arginine-conjugated bioreducible poly(disulfide amine) polymers for gene delivery systems | University of Utah | 10-Apr-12 | United States |
| MULTICELLULAR LIVING ORGANISMS | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,148,600 | Immunocompromised rodents as dual color tumor models | Anticancer, Inc. | 3-Apr-12 | United States |
| 8,153,861 | Genes for improving salt tolerance and drought tolerance of plant and the uses thereof | Biotechnology Research Institute, The Chinese Academy of Agricultural Sciences | 10-Apr-12 | China P. Rep. |
| 8,163,977 | Extra-cellular matrix localized ferritin for iron uptake, storage, and stress tolerance | Chakraborty; Niranjan | 24-Apr-12 | India |
| 8,148,605 | Biological systems input-output response system and plant sentinels | Colorado State University Research Foundation | 3-Apr-12 | United States |
| 8,148,608 | Systems and methods for clonal expression in plants | Fraunhofer USA, Inc | 3-Apr-12 | United States |
| 8,153,862 | Cytochrome P450 gene for increasing seed size or water stress resistance of plant | Myongji University Industry and Academia Cooperation | 10-Apr-12 | Korea |
| 8,148,601 | Rice blast susceptibility gene Pi21, resistance gene pi21, and uses thereof | National Institute of Agrobiological Sciences | 3-Apr-12 | Japan |
| 8,153,858 | Sale of fluorescent transgenic ornamental fish | National University of Singapore | 10-Apr-12 | Singapore |
| 8,148,604 | Methods and materials for conferring resistance to pests and pathogens of plants | Venganza Inc. | 3-Apr-12 | United States |
| NATURAL RESINS OR DERIVATIVES | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,158,754 | Multiple modified derivatives of gelatin and crosslinked material thereof | Bioregen Biomedical (Changzhou) Co., Ltd. | 17-Apr-12 | China P. Rep. |
| 8,163,883 | Gene encoding labyrinthin, a marker for cancer | Mission Therapeutics, Inc. | 24-Apr-12 | United States |
| ORGANIC COMPOUNDS | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,158,769 | Members of the capsaicin/vanilloid receptor family of proteins and uses thereof | Bayer Schering Pharma Aktiengesellschaft | 17-Apr-12 | Germany |
| 8,163,709 | TAK1-D mediated induction of cell death in human cancer cells by specific sequence short double-stranded RNAS | Board of Regents of the University of Texas System | 24-Apr-12 | United States |
| 8,153,776 | Methods and compositions for RNA interference | Cold Spring Harbor Laboratory | 10-Apr-12 | United States |
| 8,158,344 | Methods and compositions for correlating genetic markers with multiple sclerosis | Duke University | 17-Apr-12 | United States |
| 8,153,602 | Composition and methods for the pulmonary delivery of nucleic acids | Isis Pharmaceuticals, Inc. | 10-Apr-12 | United States |
| 8,153,778 | RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA) | Merck Sharp & Dohme Corp. | 10-Apr-12 | United States |
| 8,158,772 | Oligonucleotide sequences that identify species of animal | National Institute of Agrobiological Sciences | 17-Apr-12 | Japan |
| 8,163,894 | DNA for eukaryotic expression of CymR | National Research Council of Canada | 24-Apr-12 | Canada |
| 8,148,514 | hTERT gene expression regulatory gene | National University Corporation Tottori University | 3-Apr-12 | Japan |
| 8,148,513 | hTERT gene expression regulatory gene | National University Corporation Tottori University | 3-Apr-12 | Japan |
| 8,163,892 | Oncolytic virus replicating selectively in tumor cells | Oncolys Biopharma, Inc. | 24-Apr-12 | Japan |
| 8,163,893 | Pseudotyped retroviral vectors and methods of use thereof | The Regents of the University of Caifornia | 24-Apr-12 | United States |
| 8,158,766 | Genes with ES cell-specific expression | Yamanaka; Shinya | 17-Apr-12 | Japan |
| SURGERY | ||||
| Pat No | Title | Assignee | Date Issued | Country |
| 8,150,520 | Methods for catheter-based renal denervation | Ardian, Inc. | 3-Apr-12 | United States |
| 8,150,519 | Methods and apparatus for bilateral renal neuromodulation | Ardian, Inc. | 3-Apr-12 | United States |
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